Drug Substance


Vanton researches all critical pre-formulation parameters to better and more efficiently guide the product development processes and patent strategy for clients. Pre-formulation studies are on an as-needed basis to be cost-effective for clients.

  • Drug substance ‘s (DS) Solubility, Sensitivity, and Process-ability

-pH  –solvents  –heat  –shear forces  –UV Light  Moisture

  • Interactions between DS and excipient candidates

-Chemical Stability  -Physical Adsorption  –Complexation

  • Surface Activity as needed
  • Crystallinity (mostly for transdermal patch)

Drug Substance Stability

  • 40 oC/75%RH accelerated stability study
  • 25 oC/60%RH stability study or other zone configurations
  • Stress studies

Vanton Labs can help you move your product development forward.

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